This machine is a new generation of the ampoule drawing, filling and sealing combined equipment for injections. It adopts the rectangular feeding instead of the traditional ampoule feeding methods. In such case, the feeding ampoules are stable and not damaged easily. A modern clutch is mounted under the ampoule feed hopper. Therefore, the ampoule feeding can be stopped at any time while the machine is still running. So the ampoule loss can be reduces. In the part of stopping filling where changes electromagnetic switch into mechanical switch. It is reliable and durable. Bottle reverse and bottle arranging structure are used in the part of bottle out. It reduces the damage tremendously of the finished products of ampoule tremendously.